建议：FreeBSD RELENG_6
使用心得:nginx处理大并发比较稳定,特别省内存,配置简单.
1.安装python

cd /usr/ports/lang/python
make install clean 

2.安装flup

cd /usr/ports/www/py-flup 
make install clean 

3.安装django 1)

cd /usr/ports/www/py-django 
make install clean

4.安装nginx

cd /usr/ports/www/nginx
make install clean 

5.启动和管理flup的脚本 参考http://www.djangoproject.com/documentation/fastcgi/

#!/bin/sh
# Replace these three settings.
PROJDIR="/home/user/myproject"
PIDFILE="$PROJDIR/mysite.pid"
SOCKET="$PROJDIR/mysite.sock"
cd $PROJDIR
if [ -f $PIDFILE ]; then
 kill `cat -- $PIDFILE`
 rm -f -- $PIDFILE
fi
exec /usr/local/bin/python manage.py runfcgi method=prefork socket=${SOCKET} pidfile=${PIDFILE} minspare=5 maxspare=10 maxchildren=40

6.配置nginx 参考http://wiki.codemongers.com/Main
nginx.conf

user www www;
worker_processes 5;
pid /var/run/nginx.pid;
error_log /var/log/httpd/error.log warn;
events {
 worker_connections 10240;
 use kqueue;
}
http {
 include mime.types;
 default_type application/octet-stream;
 log_format main '$remote_addr - $remote_user [$time_local] '
 '"$request" $status $bytes_sent '
 '"$http_referer" "$http_user_agent" '
 '"$gzip_ratio"';
 client_header_timeout 3m;
 client_body_timeout 3m;
 send_timeout 3m;
 connection_pool_size 256;
 client_header_buffer_size 1k;
 large_client_header_buffers 4 2k;
 request_pool_size 4k;
 output_buffers 4 32k;
 postpone_output 1460;
 sendfile on;
 tcp_nopush on;
 keepalive_timeout 75 20;
 tcp_nodelay on;
 client_max_body_size 10m;
 client_body_buffer_size 256k;
 proxy_connect_timeout 90;
 proxy_send_timeout 90;
 proxy_read_timeout 90;
 client_body_temp_path /var/log/nginx/client_body_temp;
 proxy_temp_path /var/log/nginx/proxy_temp;
 fastcgi_temp_path /var/log/nginx/fastcgi_temp;
 gzip on;
 gzip_min_length 1100;
 gzip_buffers 4 32k;
 gzip_types text/plain text/html application/x-javascript text/xml text/css;
 ignore_invalid_headers on;
 include website.conf;
}

website.conf

server {
 listen 80;
 server_name test.tmdxy.org;
 access_log /var/log/httpd/access.log main;
 location / {
 # host and port to fastcgi server
 fastcgi_pass unix:/tmp/test_tmdxy.sock;
 fastcgi_param PATH_INFO $fastcgi_script_name;
 fastcgi_param REQUEST_METHOD $request_method;
 fastcgi_param QUERY_STRING $query_string;
 fastcgi_param CONTENT_TYPE $content_type;
 fastcgi_param CONTENT_LENGTH $content_length;
 fastcgi_pass_header Authorization;
 fastcgi_param REMOTE_ADDR $remote_addr;
 fastcgi_param SERVER_PROTOCOL $server_protocol;
 fastcgi_param SERVER_PORT $server_port;
 fastcgi_param SERVER_NAME $server_name;
 fastcgi_intercept_errors off;
 }
 location ^~ /media/ {
 alias /home/www/django/test_tmdxy_org/meida/;
 }
 location ~* ^.+\.(gif|png|jpg|jpeg|css|swf|htm|html|asp|php|jsp|js|doc|txt)$ {
 root /home/www/django/test_tmdxy_org/media/;
 access_log off;
 }
}

7.配置反向代理服务器
只需在server {}里加入

location /go/ {
 proxy_pass http://192.168.1.5:8088/; 
 proxy_redirect http://192.168.1.5:8088/ /;
}